Therapeutic plasma exchange (TPE), once confined to the intensive care unit and specialized apheresis suites, has migrated to the concierge clinics of the ultra-wealthy. A detailed investigative feature published today in the New York Post offers a rare glimpse into this rapidly expanding off-label application: asymptomatic, high-net-worth individuals paying $7,000–$12,000 per session to have their plasma removed and replaced with albumin solution in pursuit of systemic detoxification, inflammation reduction, and putative reversal of biological aging.