Peripheral-Microbiome Signaling in Pain and Neurodegeneration: A Multimodal Treatment Framework with David G. Changaris, MD
Learning Objectives Upon completion of this activity, participants will be able to: • Explain the role of dermal microbiome density in driving chronic pain, inflammation, and neurodegenerative cascades through TRPV-1 receptor activation and retrograde axonal transport • Describe the mechanisms by which peripheral microbiome signaling (quorum sensing molecules, biofilm metabolites) initiates central neuroinflammation and neurodegeneration …