Regenerative therapies, including platelet-rich plasma (PRP), exosome, and stem cell penile injections, combined with complementary modalities like peptides, photobiomodulation (PBM), and low-intensity extracorporeal shockwave therapy (Li-ESWT), are transforming treatments for erectile dysfunction (ED), Peyronie’s disease (PD), and cosmetic sexual health concerns. This review synthesizes clinical evidence from January 2020 to June 2025, focusing on efficacy, safety, and global adoption trends for medical professionals.
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