Inhaled CBD shrinks the size of the highly aggressive, lethal brain tumor glioblastoma in an animal model by reducing the essential support of its microenvironment, researchers report.
“We saw a significant reduction in the size of the tumor and its microenvironment was different,” Dr. Babak Baban, immunologist and associate dean for research at the Dental College of Georgia at Augusta University says, after only seven days of treatment.
Cannabidiol (CBD), a nonpsychoactive cannabinoid with a low toxicity profile, has been shown to produce antitumor activity across cancers in part through selective production of reactive oxygen species (ROS) in tumor cells. The alkylating agent, temozolomide (TMZ), is standard of care for treatment of glioblastoma (GBM). It can trigger increased ROS to induce DNA damage. It has also been reported that downregulating the expression of RAD51, an important DNA damage repair protein, leads to sensitization of GBM to TMZ.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962752/
Doctor Jeff Hergenrather has been a general practitioner since 1976. He’s experience is in general medicine, OB-GYN, pediatrics, neonatal care, and emergency medicine. His practice as a cannabis consultant and general medicine consultations started in 1999. Since then he’s consulted for people worldwide.
At the Sharefax community event Jeffrey Hergenrather shared information about Cannabis & Cannabinoids opportunities and limitation in medical practice. His presentation took viewers through a basic overview of the endocannabinoid system as well as
many other topics that are newly being released and shared openly for those curious about improving their health with cannabis.
Sean Mcallister presents "Cannabinoids as Antitumor Agents: Moving Toward the Clinic" at CannMed 2017. Join us for CannMed 2018, taking place October 22-24, 2018 at the brand-new UCLA Luskin Conference Center. This industry-leading event will feature 7 expert panels and 31 presentations from Raphael Mechoulam, Ethan Russo, Bonni Goldstein, Dustin Sulak, Kevin McKernan, Staci Gruber, David Meiri, Jeff Chen and more. Learn more at www.cannmedevents.com.
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