Oct 20, 2024 8:49 am
- Deprescribing antihypertensives was associated with a 12% lower likelihood of progressing to a worse CFS per 12-week period (odds ratio [OR], 0.88; 95% CI, 0.78-0.99) compared with stable users.
- Among residents with dementia, deprescribing was associated with a 16% reduced likelihood of cognitive decline per 12-week period (OR, 0.84; 95% CI, 0.72-0.98).
- At the end of follow-up, 12% of residents had a higher CFS score and 7.7% had a lower CFS score.
- In the intention-to-treat analysis, the association between deprescribing antihypertensive medications and reduced cognitive decline remained consistent (OR, 0.94; 95% CI, 0.90-0.98).