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Combined Adaptive Immune Mechanisms Mediate Cardiac Injury After COVID-19 Vaccination

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Dr. West

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Nov 07, 2025 9:37 am

(@Dr. West)

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The COVID-19 pandemic, caused by SARS-CoV-2, has led to the first approval of mRNA vaccines in humans. By producing the full-length SARS-CoV-2 Spike protein, they induce protective antiviral immunity. Acute myopericarditis (AMP) development after vaccination has repeatedly been reported; however, the pathogenesis of this complication remains elusive.

https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.125.074644

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mrna vaccine acute myopericarditis molecular mimicry t-cell autoimmunity cmet homing

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