Back in 1907, American biologist Henry Van Peters Wilson discovered that sponges will re-form into living creatures after their cells are broken apart through a fine mesh screen — demonstrating that the cells of living organisms contained something telling them how to build complex, multi-cellular structures.
Researchers dined out this for decades, and their subsequent discoveries led to the isolation of pluripotent stem cells — “master cells” that can divide endlessly and become any type of cell in the body — first from mouse embryos in 1981, then from human embryos in 1998.