There are two proteins implicated in Alzheimer's: amyloid and tau. Most of the drugs—included those recently approved by the US Food and Drug Administration (FDA)—focus on removing amyloid. To date, though, there has been little focus on removing tau "tangles." However, the new nasal spray, developed by researchers at the University of Texas Medical Branch, focuses on this protein. Nasal spray clears proteins linked to Alzheimer's, study finds (medicalxpress.com)