Oct 03, 2025 7:40 am
Rapamycin was first discovered in bacteria living in Easter Island soil in the 1970s, and medical professionals now use it to prevent organ-transplant rejection, as it is a powerful immunosuppressant. It works by blocking a molecular switch that tells cells when nutrients are abundant.
Metformin, meanwhile, is a synthetic descendant of a compound found in French lilac (also known as goat's rue) and is widely prescribed to control blood sugar in type 2 diabetes. Both drugs are involved in the body's ability to sense nutrients and energy, so biologists like us hoped they might copy the mechanisms activated by eating less.
https://www.sciencealert.com/scientists-confirm-anti-aging-drug-appears-to-prolong-life
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