Health officials have long warned that gonorrhea is becoming more and more resistant to all the antibiotic drugs we have to fight it. Last year, the US reached a grim landmark: For the first time, two unrelated people in Massachusetts were found to have gonorrhea infections with complete or reduced susceptibility to every drug in our arsenal, including the frontline drug ceftriaxone. Luckily, they were still able to be cured with high-dose injections of ceftriaxone. But, as the US Centers for Disease Control and Prevention bluntly notes: "Little now stands between us and untreatable gonorrhea."

https://arstechnica.com/science/2024/03/super-gonorrhea-rate-quickly-triples-in-china-now-40x-higher-than-us/

https://www.theguardian.com/society/article/2024/aug/15/gonorrhoea-getting-more-drug-resistant-and-may-become-untreatable

https://www.yahoo.com/lifestyle/super-gonorrheais-rare-but-the-sti-is-smart--and-doctors-are-concerned-213856598.html