Senescent cells are a hallmark of aging. They have also been implicated in a broad spectrum of age-related diseases and conditions including cancer, diabetes, cardiovascular disease, and Alzheimer’s disease. Senolytics are compounds that selectively induce apoptosis, or programmed cell death, in senescent cells. Despite their potential promise, most senolytic compounds identified to date have been hampered by poor bioavailability and adverse side effects.
Three Novel Anti-Aging Senolytics Discovered Using AI and Synbio (genengnews.com)