A New Paradigm in EnergyManagement

Mitochondria, NAD+, and the concept of adrenal fatigue are closely interconnected within the context of energy metabolism and stress physiology. Mitochondria are pivotal for ATP production and steroid hormone synthesis, including cortisol, while the coenzyme NAD+ is essential for mitochondrial function and energy homeostasis. We explore the concept of addressing mitochondrial dysfunction as a clinical tool when addressing patients with adrenal fatigue.

Who is Dr. Chris Meletis?

Dr. Chris D. Meletis is an educator, international author and lecturer. His personal mission is “Changing World’s Health One Person at a Time.”

Dr. Meletis believes that when people become educated about their body is the moment when change begins. He has authored 16 books and over 200 national scientific articles in such journals and magazines as Natural Health, Alternative and Complementary Therapies, Townsend Letter for Doctors and Patients, Life Extension and Natural Pharmacy. Dr. Meletis served as Dean of Naturopathic Medicine and Chief Medical Officer for 7 years and was awarded the 2003 physician of the year by the American Association of Naturopathic Physicians.

Learning Objectives

Participants will:

• Review the research on Oxaloacetate as an FDA approved Medical Food for Long Covid
• Mitochondrial dysfunction can impair cortisol synthesis, contributing to symptoms like fatigue, brain fog, and reduced stress resilience.
• Low NAD+ levels are correlated with stress-related conditions, impairing mitochondrial function, lowering ATP yield, and perpetuating fatigue.
• Activation of sirtuins—proteins that maintain mitochondrial health, repair DNA, and mitigate cellular stress.
• Fueling mitochondrial energy production.
• A recap of steroidogenesis starting with cholesterol and pregnenolone, and the role of the mitochondrion.