Muscle Centric Health By Dr Robert Quinn

Muscle-Centric Medicine redefines insulin resistance as a skeletal muscle disease, not a pancreatic one. While the pancreas produces insulin, muscle determines whether insulin works, as it is the primary site of glucose uptake and metabolic control.

Insulin resistance begins in muscle through mitochondrial dysfunction, redox imbalance, receptor oxidation, inflammation, and fibrosis—long before blood sugar rises.

By restoring muscle function at the tissue level, this model offers a unified clinical framework to prevent and reverse diabetes, obesity, cardiovascular disease, cancer metabolism, and accelerated aging.