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Type 1 diabetes affects 46.3 million people worldwide, and the number of people affected increases by about 3% each year. It requires careful calculations of insulin needs and bothersome daily injections to avoid peripheral diseases caused by extremes of high or low blood sugar. Automated insulin delivery systems, also called artificial pancreases, make diabetes management …
Image Caption: T cells are a type of white blood cell that play a central role in the immune response. Photo credit: NIAID. When you need a bit of motivation, it often has to come from within. New research suggests cancer-fighting immune cells have found a way to do just that. Scientists at the University …
Image Caption: Northwestern Medicine scientists led by Adam Sonabend report results of the first-in-human clinical trial using a skull-implantable ultrasound device to open the blood-brain barrier and repeatedly permeate large, critical regions of the human brain to deliver chemotherapy. Image Credit: Northwestern University News Release Highlights: The first-in-human trial used a novel ultrasound device to …
Researchers have long been working on how to treat obesity, a serious condition that can lead to hypertension, diabetes, chronic inflammation, and cardiovascular diseases. Studies have also revealed a strong correlation of obesity and cancer — recent data show that smoking, drinking alcohol, and obesity are the biggest contributors to cancer worldwide. The development of …
Like elite firefighters headed into the wilderness to combat an uncontrolled blaze, probiotic bacteria do a better job quelling gut inflammation when they’re equipped with the best gear. A new study by researchers at the University of Wisconsin-Madison demonstrates just how much promise some well-equipped gut-friendly bacteria hold for improving treatments of inflammatory bowel disease …
Cell-based therapies have long been thought of as an alternative treatment option for patients with a range of diseases caused by organ and tissue failure, inclusive of heart attack, diabetes, corneal blindness, and cystic fibrosis. While great in theory, in practice, these therapies show limited clinical success in many applications due to low cell viability …
Standard chemotherapies may efficiently kill cancer cells, but they also pose significant risks to healthy cells, resulting in secondary illness and a diminished quality of life for patients. To prevent the previously unavoidable damage, researchers, led by Penn State, have developed a new class of nanomaterials engineered to capture chemotherapy drugs before they interact with …
Chimeric antigen receptor (CAR) T cell therapy is a type of immunotherapy that uses genetically modified versions of a person’s own immune cells to fight cancer. Current models of CAR T cells have several limitations, including a tendency to stop working after a period of time. A team of scientists at MSK’s Sloan Kettering Institute …
The COVID-19 pandemic highlighted the devastating impact of acute lung inflammation (ALI), which is part of the acute respiratory distress syndrome (ARDS) that is the dominant cause of death in COVID-19. A potential new route to the diagnosis and treatment of ARDS comes from studying how neutrophils — the white blood cells responsible for detecting …
Anthrax has a scary reputation. Widely known to cause serious lung infections in humans and unsightly, albeit painless, skin lesions in livestock and people, the anthrax bacterium has even been used as a weapon of terror. Now the findings of a new study suggest the dreaded microbe also has unexpected beneficial potential — one of …