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Exercise Promotes Healthy Cellular Signals

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Vigorous exercise raises osteocalcin levels, a hormone associated with bone heath, insulin sensitivity and fat stores.

Exercise encourages cellular communications among bone, fat, and pancreatic cells.  Norman Pollack, from Georgia Health Sciences University (Georgia, USA), and colleagues completed a study of obese children enrolled in after-school exercise programs. The researchers found that 12 weeks of vigorous exercise produced stronger bones, improved insulin sensitivity (reduced diabetes risk) and less of the most-deadly belly (visceral) fat. The team observed that blood levels of the hormone osteocalcin, made by bone-producing osteoblasts, were raised by vigorous exercise, and thereby may explain the response among bone, fat, and pancreatic cells.  

Norman K Pollock; Paul J Bernard; Bernard Gutin; Catherine L Davis; Haidong Zhu; Yanbin Dong.  “Adolescent obesity, bone mass, and cardiometabolic risk factors.”  The Journal of Pediatrics 2011;158(5):727-34.