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For some peptides, killing bacteria is an inside job

BioTech CEO Cites Antimicrobial Resistance ‘Arms Race’ Advancements as the Post-Antibiotic Era Ensues

Peptides could be primed to solve the knotty problem of antibiotic resistance among humans. Rice University scientists believe they can help. The Rice lab of chemist Anatoly Kolomeisky modeled a range of antimicrobial peptides (AMPs), natural and varied molecules that aid biological systems, to evaluate the mechanisms they use to stop harmful bacteria. That understanding …

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CRISPR Contrives Secret Lives Of Antimicrobial Peptides

CRISPR Contrives Secret Lives Of Antimicrobial Peptides

Scientist have developed a way to examine how antimicrobial peptides behave in an in vivo setting rather than the typical in vitro setting by using a systematic strategy, as published in eLife. CRISPR-Cas9 gene editing technology was used to systematically delete AMP genes, going as far to delete all the known AMPs in fruit fly …

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