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IMAGE: Scanning electron micrograph of a human neutrophil ingesting MRSA (yellow). Credit: NIAID A clinical trial to test the antibiotic dalbavancin for safety and efficacy in treating complicated Staphylococcus aureus (S. aureus) bacteremia has begun. The trial will enroll 200 adults hospitalized with complicated S. aureus infection at approximately 20 trial sites around the United …
The FDA has recently lifted the clinical holds placed on the phase ½ clinical trial of Solid Biosciences’s gene therapy treatment for Duchenne muscular dystrophy; a clearance was secured to resume dosing in the trial after making manufacturing changes to the number of viral particles that are given to patients. The adeno-associated viral vector-mediated gene …
The FDA has announced that it is lifting the hold and cleared ImStem’s investigational drug IMS001 which utilizes AgeX’s pluripotent stem cell technology ESI-053, thus it will be allowed to be made available for the treatment of multiple sclerosis in clinical trial settings. “Since pluripotent stem cells are capable of differentiating into all human cell …
Umbilical cord blood has been revealed to be a viable alternative source of hematopoietic stem cell transplantation in patients with blood cancers, but it is not without limitations including a small number of usable cells and slow immune reconstitution which may put patients at risk of infection. University of Montreal researchers identified a small molecule …
The first patient has been enrolled in a new clinical trial designed to test effectiveness of using precise, higher dose MRI guided radiation therapy to treat pancreatic cancer by the Henry Ford Cancer Institute. The National Cancer Institute estimates 55,000 new cases of pancreatic cancer to have been diagnosed in 2018, with a 5 year …