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Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours — sometimes more than a day — in a reversible intermediate state, according to a discovery by researchers at Weill Cornell Medicine. Their revelation of this fundamental …
Osaka City University research has found that metolazone, a common antihypertensive medication that has been used for the past 5 decades, is able to jumpstart lifespan-extending cellular repair processes in roundworms; findings published in the journal Biogerintilogy suggest that this mechanism could translate to humans offering new pathways in the hunt for an anti-aging drug. …
Canadian scientists elucidate the mechanism of PNKP, a DNA repair enzyme, paving the way for innovations in targeted cancer therapies. In normal cells damaged DNA can lead to the breakdown of chromosomes and, ultimately, cancers. On the other hand, damaging DNA in cancer cells is a useful way to eradicate them. A long-term goal of …
University of Rochester (US) scientists discover how DNA maintenance is regulated, opening the door to interventions that may enhance the body’s natural preservation of genetic information. University of Rochester (US) scientists discover how DNA maintenance is regulated, opening the door to interventions that may enhance the body’s natural preservation of genetic information. The new findings …
Vitamin supplements may reduce the risk of breast cancer by about 30%, whereas calcium supplements potentially reduce the risk by 40%. Breast cancer is the most common cancer in women, with over one million new cases diagnosed annually worldwide. Jaime Matta, from the Ponce School of Medicine (Puerto Rico), and colleagues studied data collected on …