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According to a news media release, a single hormone appears to coordinate the lifespan extension produced by a low-protein diet. A new study from Pennington Biomedical Research Center, published in the journal Nature Communications, found that reducing the amount of protein in the diet produced an array of favorable health outcomes, including an extension of …
A new study has revealed an antibody mimetic of fibroblast growth factor 21 (FGF21) that is safe and effective in reducing the weight of obese patients in a recent clinical study. Led by Puneet Arora (Principia Biopharma, CA, USA), the team first conducted trials in non-human primates before moving on to a small clinical trial …
New roles for BP3 have been shown for regulating carbohydrate and lipid metabolism that overlaps effects of endocrine FGF19 and FGF21; BP1 and BP3 proteins share cysteine residues but have distinct C terminal FGF binding domains, as published in Scientific Reports. Fibroblast growth factor binding protein 3 binds to FGF19, FGF21, and FGF23; interaction between …
Researchers have come closer to understanding the diverse effects of different forms of training, showing that cardio training on an exercise bike causes up to 3 times as much increase in production of FGF21 hormones which has positive effects on metabolism than that of strength training with weights, as published in the Journal of Clinical …
Cardio exercises and strength training affect the body differently with regards to types of hormones released into the blood, such as cardio exercises produces a greater amount of metabolic hormone FGF21 than strength training does, as published in the Journal of Clinical Investigation–Insight. Regardless of what form of exercise done it is done to improve …
A surprising discovery has been made by researchers at the University of Copenhagen that a particular craving for sweet things may be determined by genetic variations, it has been found that individuals with this genetic disposition for sweet tooth have less body fat, as published in Cell Reports. Individuals with a gene variation on FGF21 …
Klotho proteins, namesake of the Greek goddess who spun the threads of life, play a key role in the regulation of metabolism and longevity. The 3 dimensional structure of beta-Klotho was revealed by researchers at Yale University illuminating its therapeutic potential and intricate mechanism. As published in Nature Klotho proteins have the great potential …