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New roles for BP3 have been shown for regulating carbohydrate and lipid metabolism that overlaps effects of endocrine FGF19 and FGF21; BP1 and BP3 proteins share cysteine residues but have distinct C terminal FGF binding domains, as published in Scientific Reports. Fibroblast growth factor binding protein 3 binds to FGF19, FGF21, and FGF23; interaction between …
High levels of the hormone FGF23 has been linked to changes in brain structure; they are associated with structural changes in the frontal lobes, as published in the journal PLoS ONE. Medical University of South Carolina researchers have uncovered mechanisms by which high levels of the hormone FGF23 reduces brain health. High levels of fibroblast …
Researchers from UT Southwestern published in Nature the molecular structure of alpha Klotho and how the anti-aging protein transmits a hormonal signal that controls a variety of biological processes in collaboration with the University of New York and Wenzhou University. Mice lacking in either a-Klotho or hormone FGF23 were demonstrated 2 decades ago to suffer …