Since 1996 WHN is the second oldest medical website on the net, second only to the American Medical Association, servicing over 35,000 physicians and scientists worldwide.
Non-Profit Trusted Source of Non-Commercial Health Information
Research At A Glance: Children who regularly ate peanut-containing foods early in life had a greatly reduced risk of developing peanut allergy into adolescence. Introducing peanut-containing foods as early as 4 to 6 months of age could potentially prevent tens of thousands of cases of peanut allergy each year. Peanut allergy is one of the …
Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel immunotherapy combination, targeting checkpoints in both T cells and myeloid suppressor cells, that successfully reprogrammed the tumor immune microenvironment (TIME) and significantly improved anti-tumor responses in preclinical models of pancreatic cancer. In this study, published today in Nature Cancer, researchers used …
A patient’s own immune cells, multiplied into an army of billions of immune cells in a lab, can be used as a living medicine against metastatic melanoma, an aggressive form of skin cancer, as the TIL trial has shown. The TIL trial is the world’s first comparative phase 3 trial looking into the effect of …
Research matters highlights: An experimental approach that combines cat allergy shots with a monoclonal antibody led to more effective relief that continued a year after treatment ended. This approach might also be effective for other types of allergies, including food allergies For people with cat allergies, exposure to these furry creatures can lead to a …
A University of Minnesota Twin Cities team has, for the first time, developed a new tool to predict and customize the rate of a specific kind of DNA editing called “site-specific recombination.” The research paves the way for more personalized, efficient genetic and cell therapies for diseases such as diabetes and cancer. The study is …
Micronutrient deficiencies can promote inflammation and render the immune system particularly sensitive to allergenic substances. In particular, iron deficiency signals danger to immune cells and leads to a more pronounced, exaggerated immune response. For the first time, scientists at the Messerli Research Institute of MedUni Vienna, Vetmeduni Vienna and the University of Vienna conducted a …
Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting. The study, published in the peer-reviewed journal Cell Reports, could lead to improved treatments for soft-tissue sarcomas. The researchers focused on the tumor microenvironment — an ecosystem of blood vessels and other …
On April 20, 2022, researchers at the Sloan Kettering Institute reported in the journal Nature that a recently discovered new immune cell “soldier” could be a good target for immunotherapy, raising hopes that it might help narrow the gap between people who respond and those who do not. The new cells, which the scientists have …
Pancreatic cancer is one of the most aggressive and deadly tumor types and is notorious for its resistance to virtually all types of treatment, including newer immunotherapies. A new study — in mice — from Washington University School of Medicine in St. Louis suggests that blocking a major inflammatory pathway that is activated in pancreatic …
Chimeric antigen receptor (CAR) T cell therapy is a type of immunotherapy that uses genetically modified versions of a person’s own immune cells to fight cancer. Current models of CAR T cells have several limitations, including a tendency to stop working after a period of time. A team of scientists at MSK’s Sloan Kettering Institute …