Mature Heart Muscle Cells from Stem Cells
University of Wisconsin/Madison (US) team utilizes micropatterned substrates to successfully culture cardiomyocytes. To-date, researchers have been able to differentiate human embryonic stem cells (hESC) into immature heart muscle cells. But these cells are unable to develop the robust internal structures—repeating sections of muscle cells called sarcomeres—that enable cardiomyocytes, mature heart muscle cells, to produce the …