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Researchers Discover How Sound Reduces Pain In Mice

Researchers Discover How Sound Reduces Pain In Mice

An international team of scientists has identified the neural mechanisms through which sound blunts pain in mice. The findings, which could inform the development of safer methods to treat pain, were published in Science. The study was led by researchers at the National Institute of Dental and Craniofacial Research (NIDCR); the University of Science and …

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Mouse Fetuses Generated Without Eggs Or Sperm

Mouse Fetuses Generated Without Eggs Or Sperm

Artificial embryos that were created without using sperm or eggs were observed to have started to form live fetuses after being implanted into female mice for the first time; embryos did have some malformations and this approach is still a very long way from being applicable to human babies.  The artificial mouse embryos were created …

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Protein Cocktail Makes Mice Regenerate Toes

Discovery of a New Compound Turns on a Longevity Gene in Mice

Scientists from Texas A&M University have now figured out how to regrow bone and joints of a mouse’s amputated toes, much like a lizard would, as published in the journal Nature Communications. Mammals typically do not regenerate body parts, this development may one day lead to medical procedures in which amputees are able to grow …

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Deep Brain Genetic Manipulation

REGULACIÓN DE GRASA LOCALIZADA POR UN GEN

Results of 5 years of research by bio-imaging and optogenetics has developed a noninvasive light sensitive photoactivatable recombinase suitable for genetic manipulation in vivo that was presented by the Korea Advanced Institute of Science and Technology, as published in Nature Communications. Highly light sensitive property of photoactivatable Flp recombinase will be ideal for controlling genetic …

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Fluorescence Light Up Potential Antisense Oligo Drugs For MD

Fluorescence Light Up Potential Antisense Oligo Drugs For MD

A fluorescent mouse model of myotonic muscular dystrophy type 1 has been developed by researchers at Massachusetts General Hospital which may lead to finding new treatments for the genetic disorder, as published in Nature Communications. Initial studies using the genetically engineered mice have shown how modified forms of antisense oligonucleotides can target and correct the …

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Antibodies Treat Alzheimer’s-Like Disease in Mice

Antibodies Treat Alzheimer’s-Like Disease in Mice

Newly identified anti-tau antibodies have been shown to prevent the accumulation of toxic tau proteins in the brains of mice. A newly discovered antibody treatment has been shown to stop a toxic protein linked to Alzheimer’s disease from accumulating in the brains of mice. Drs. David Holtzman and Marc Diamond of Washington University School of …

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