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How herpes checks into the nervous system for life

Differences in herpes virus symptoms may relate to variations in strain gene expression

Herpes-type 1 is sealed with a kiss for a lifetime. More than half of U.S. adults are carriers of HSV1 (herpes simplex virus type 1) which hibernates in the peripheral nervous system and can never be eradicated. A new Northwestern Medicine study published in Nature has uncovered the virus’s sneaky strategy for infecting the nervous …

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Discovery Illuminates How Brain Cells Die In Prion Diseases

Defending Against Prion Diseases

Researchers show how toxic aggregates are formed inside brain cells, and how to block the cell-killing process—which may also be at work in Alzheimer’s and other neurodegenerative diseases. Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP. How these aggregates form …

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