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Calorie Restriction Builds Strong Muscles And Stimulates Healthy Aging Genes

Calorie Restriction Builds Strong Muscles And Stimulates Healthy Aging Genes

According to recent research, reducing your overall calorie intake may help to rejuvenate your muscles and activate anti-aging biological pathways that are important to optimal health. Decreasing calories without depriving the body of essential vitamins and minerals has been long known to delay the progression of age-related diseases, in animal studies, however, this study published …

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Researchers develop messenger RNA therapy for ovarian cancer, muscle wasting

Scientists Discover Cancer Trigger That Could Spur Targeted Drug Therapies

Researchers at Oregon State University and Oregon Health & Science University have developed a promising, first-of-its-kind messenger RNA therapy for ovarian cancer as well as cachexia, a muscle-wasting condition associated with cancer and other chronic illnesses. The treatment is based on the same principles used in SARS-CoV-2 vaccines, and the scientists say mRNA technology, though …

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Biochemistry researchers repair and regenerate heart muscle cells

Caught In The Crossfire

Researchers at the University of Houston are reporting a first-of-its-kind technology that not only repairs heart muscle cells in mice but also regenerates them following a heart attack, or myocardial infarction as its medically known. Published in the Journal of Cardiovascular Aging, the groundbreaking finding has the potential to become a powerful clinical strategy for …

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Researchers map human sensory neurons, pursue chronic pain cure

Around the World, Too Little Relief for Pain

An investigation into how human nerve cells differ from animal cells has provided researchers from The University of Texas at Dallas’ Center for Advanced Pain Studies (CAPS) with important clues in the pursuit of more effective treatments for chronic pain. Dr. Ted Price BS’97, Ashbel Smith Professor of neuroscience in the School of Behavioral and …

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DNAzymes – How Active DNA Molecules With Therapeutic Potential Work

Long-range four-stranded DNA structures found to play a role in rare aging disease

DNAzymes are precision biocatalysts that destroy unwanted RNA molecules. However, major obstacles to their use in medicine remain. Together with Jülich Research Centre (FZJ) and the University of Bonn, a research team from Heinrich Heine University Düsseldorf (HHU) has investigated with atomic resolution how DNAzymes work in real-time. They have now presented these important fundamental …

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Study Identifies Factor In ‘Young Blood’ That Helps Rejuvenate Aged Mouse Muscle

End To End Blood Testing Device

As we age, our muscles gradually become smaller, weaker, and less able to heal after injury. In a new study, UPMC and University of Pittsburgh researchers pinpoint an important mediator of youthfulness in mouse muscle, a discovery that could advance muscle regeneration therapies for older people. Published in Nature Aging, the study demonstrates that circulating …

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Experimental mRNA HIV Vaccine Shows Promise In Animals

Experimental mRNA HIV Vaccine Shows Promise In Animals

Image: Scanning electromicrograph of an HIV-infected H9 T cell. Image Credit: NIAID An experimental HIV vaccine based on mRNA — the same platform technology used in two COVID-19 vaccines — shows promise in mice and non-human primates, according to scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes …

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Promising treatment for Alexander disease moves from rat model to human clinical trials

Fixing Protein Production Errors Lengthens Lifespan

Alexander disease is a progressive and rare neurological disorder with no cure or standard course of treatment. But a new study led by researchers at the University of Wisconsin-Madison involving a rat model of the disease offers a potential treatment for the typically fatal condition. It’s a significant step in efforts to help people with …

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LOW-COST, PORTABLE DEVICE COULD DIAGNOSE HEART ATTACKS IN MINUTES

LOW-COST, PORTABLE DEVICE COULD DIAGNOSE HEART ATTACKS IN MINUTES

Researchers from the University of Notre Dame and the University of Florida have developed a sensor that could diagnose a heart attack in less than 30 minutes, according to a study published in Lab on a Chip. Currently, it takes health care professionals hours to diagnose a heart attack. Initial results from an echocardiogram can …

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How Long-Known Genes Continue To Surprise Researchers

DNA-Editing Method Shows Promise To Treat Mouse Model Of Progeria

Alternative splicing can lead to the formation of numerous protein variants. For the first time, alternative splicing has now been systematically analysed for the family of glutamate receptors. Proteins are encoded by genes — however, this information is divided into small coding sections, which are only assembled during a process called splicing. Various combinations are …

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