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A common mutation in gliomas sensitizes them to immunotherapy, a finding which researchers believe could have broader therapeutic implications for all glioma patients. A single common genetic mutation, or error, may hold the key to making immunotherapy more effective against gliomas, according to new mouse model findings from the University of Michigan Health Rogel Cancer …
In a study of more than 400 adults with normal blood pressure, those who had high levels of stress hormones detected in their urine were more likely to develop high blood pressure over the next 6-7 years. Higher levels of the stress hormone cortisol were also linked to an increased risk of cardiovascular events, including …
Emerging findings from intervention studies implicate healthy dietary patterns combined with lifestyle modifications have the potential to prevent and treatment mental health disorders and modify drug treatment effects. There is strong evidence that nutritional patterns can affect later-life brain function; a healthy diet filled with high-quality foods has been linked to reductions in cognitive decline …
During development, brain cells may find different ways to connect with each other based on sex, according to researchers at the Marshall University Joan C. Edwards School of Medicine. The study, recently published in eNeuro, an open-access journal for the Society of Neuroscience, showed a significantly more robust synaptogenic response in male-derived cells compared to …
Malnourished children who received a food supplement designed to boost normal gut microbes gained more weight than those given a standard nutritional supplement. The microbiome-targeted supplement also raised levels of proteins in the blood associated with bone, cartilage, and brain health. Longer studies are needed to see if these improvements lead to better physical and …
An analysis found that almost 14% of older adults with dementia had long-term prescriptions for three or more medications that affect the nervous system. Such drug combinations can raise the risk of dangerous side effects, and in some cases hasten cognitive decline. The hallmark of dementia is loss of memory and other cognitive abilities. People …
Neurons lack the ability to replicate their DNA, so they’re constantly working to repair damage to their genome. Now, a new study by Salk scientists finds that these repairs are not random, but instead focus on protecting certain genetic “hot spots” that appear to play a critical role in neural identity and function. The findings, …
Why do some people with cold sores around their lips experience painful lesions, while others have no symptoms at all, yet still spread the virus? A new study conducted at Penn State finds that these differences could be due to variations in the way certain strains of herpes simplex (HSV-1) — the virus that causes …
A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations and mutations, epigenetic alterations, mitochondrial dysfunction, endocrine disruption, altered intercellular communication, altered microbiome communities, and impaired nervous system function. The study by researchers at Columbia University …
A new study shows that stress really can give you gray hair. Researchers found that the body’s fight-or-flight response plays a key role in turning hair gray. Your hair color is determined by pigment-producing cells called melanocytes. New melanocytes are made from melanocyte stem cells that live in the hair follicle at the base of …