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parkinsons

Parkinson’s Disease, Examining Clinical Approaches

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Parkinson's Disease

Parkinson’s disease (PD) is characterized as a progressive neurodegenerative disorder associated with the loss of dopamine-producing neurons in the substantia nigra region of the midbrain. Classically its presentation includes a triad of motor manifestations: bradykinesia, resting tremor, and muscle rigidity. Among non-motor manifestations are autonomic dysfunction, mood disorders, and cognitive impairment. The prevalence of PD has doubled in the past …

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Sesaminol prevents Parkinson's disease by activating the Nrf2-ARE signaling pathway

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Sesaminol prevents Parkinson's disease by activating the Nrf2-ARE signaling pathway

Parkinson’s disease (PD) is a neurodegenerative disease with symptoms of bradykinesia, rigidity, tremor, and postural reflex disorder, due to a decrease in brain dopamine production resulting from the degeneration and loss of dopaminergic neurons in the substantia nigra. Previous studies showed the involvement of neurotoxins, oxidative stress, and mitochondrial disorders as causes of degeneration of …

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Could a Tapeworm Medication Help Parkinson’s Disease?

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Could a Tapeworm Medication Help Parkinson’s Disease?

The National Institutes of Health (NIH) says that over half a million people have Parkinson’s disease in the US with approximately 50,000 new diagnoses per year. While there is no cure as yet scientists around the world are looking for treatments and cures. The National Institutes of Health (NIH) says that over half a million …

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Lab-Grown Brain Cells Hold Promise to Treat Neurological Conditions

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Lab-Grown Brain Cells Hold Promise to Treat Neurological Conditions

Researchers successfully grow a key type of human brain cell in the laboratory, and successfully transplant it for further maturation in the brains of mice. The medial ganglionic eminence (MGE) cell is a type of human nerve-cell progenitor that plays a key role in neurodegenerative disorders ranging from Alzheimer’s to Parkinson’s diseases, epilepsy, and spinal …

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Diabetes Drug Tackles Neurodegenerative Diseases

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Diabetes Drug Tackles Neurodegenerative Diseases

A drug that controls type-2 diabetes may help to repair spinal cords affected by inherited neurodegenerative disease, in a mouse model. Pioglitazone , a drug that controls type-2 diabetes may repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death.  Aurora …

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Enhancing “Cellular Garbage Disposal” May Extend Lifespan

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Increasing the expression of a gene previously linked to Parkinson’s disease has be shown in increase the lifespan of fruit flies by as much as 25%. A team of scientists from UCLA have discovered that a gene previously implicated in Parkinson’s disease can delay the onset of aging and extend the healthy lifespan of fruit …

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Vitamin D May Impact Parkinson’s Disease

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Vitamin D May Impact Parkinson’s Disease

Dietary supplementation of Vitamin D may slow the neurodegenerative effects of Parkinson’s Disease, among those afflicted who have a particular genotype. Parkinson’s Disease (PD) is a brain disorder that causes tremors and difficulty with movement and walking, and most commonly affects people over the age of 50.  Masahiko Suzuki,from the Jikei University School of Medicine …

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Tai Chi Assists Balance in Parkinson’s

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Tai Chi Assists Balance in Parkinson’s

Parkinson’s Disease patients who practice tai chi enjoy greater limits of stability and better sensory organization. Parkinson’s Disease (PD) is a brain disorder that causes tremors and difficulty with movement and walking, and most commonly affects people over the age of 50. A slow, meditative, physical practice, tai chi originated as a martial art but …

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Endometrial Stem Cells Repair Parkinson's Brain Damage

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Endometrial Stem Cells Repair Parkinson's Brain Damage

Endometrial stem cells have been shown to restore dopamine production in a mouse model of Parkinson’s disease. Preliminary study results offer hope of a new treatment for women with Parkinson’s disease. Professor Hugh S Taylor of Yale School of Medicine and colleagues colleted and cultured endometrial stem cells obtained from 9 women. Tests showed that …

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