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Image: Killer T cells surround a cancer cell (Photo Credit: National Institutes of Health) Before a patient can undergo T-cell therapy designed to target cancerous tumors, the patient’s entire immune system must be destroyed with chemotherapy or radiation. The toxic side effects are well known, including nausea, extreme fatigue, and hair loss. Now a research …
Chimeric antigen receptor (CAR) T cell therapy is a type of immunotherapy that uses genetically modified versions of a person’s own immune cells to fight cancer. Current models of CAR T cells have several limitations, including a tendency to stop working after a period of time. A team of scientists at MSK’s Sloan Kettering Institute …
Kratom is a Southeast Asian tree that has been used in traditional medicine for pain relief among others. Use has spread to Europe and America and is showing promise in treatment for pain and opioid addiction. New research suggests that a metabolite of a kratom alkaloid may be behind the therapeutic effects, as published in …
Brain proteins and patterns reveal clues to what could be new understandings of epilepsy, new therapies could be in the future for patients living with anxiety or epilepsy due to the breakthrough discovery from the researchers at UNLV Tufts University School of Medicine, as published in Nature Communications. The new study showing how proteins interact …
A non-opioid investigational drug has been found to inhibit macrophage receptor on immune cells which may relieve pain particularly in cases with chronic neuropathic pain conditions such as diabetic neuropathy, as published in The Journal of Neuroscience. In an effort to address the opioid addiction epidemic researchers having been working to find alternative strategies …
A new form of depression has been identified by researchers at Hiroshima University that could be used to inform a new generation of treatments and shed light on how RGS8 protein may be involved in depressive behavior, as published in the journal Neuroscience. 90% of antidepressant drugs are based on the monoamine hypothesis, thought to …