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Cancer treatments often struggle with balancing efficacy and side effects. A new study by EPFL scientists offers a promising solution using antibody-peptide inhibitor conjugates to target specific cell types and block the activity of cancer-promoting enzymes called cathepsins. Tumor cells often hijack normal physiological processes to support their growth, exploiting proteins that are in charge …
Columbia University researchers have found cells inside clogged arteries share similarities with cancer and aggravate atherosclerosis, raising the possibility that anticancer drugs could be used to treat atherosclerosis and prevent heart attacks. Their study found that smooth muscle cells that normally line the inside of our arteries migrate into atherosclerotic plaques, change their cell identity, …
A drug used to treat children with epilepsy prevents brain tumor formation and growth in two mouse models of neurofibromatosis type 1 (NF1), according to a study by researchers at Washington University School of Medicine in St. Louis. NF1 is a genetic condition that causes tumors to grow on nerves throughout the body, including the …
Scientists from St. Jude’s Children’s Research Hospital report reversing an aggressive form of cancer called Rhabdoid, and reverting malignant cells towards a more normal state, their findings are published in Nature, and they could have implications for other cancers that are driven by the loss of a tumor suppressor. “Rather than making a toxic event …
According to a news release, age-related changes that cause the skin to stiffen and become less elastic may also contribute to higher rates of metastatic skin cancer in older people, according to research by investigators from the Johns Hopkins Kimmel Cancer Center. The study, published March 12 in Nature Aging, shows that increased stiffness in …
Whenever we cut ourselves stem cells rush to the rescue, growing new epidermis to cover the wound. But only some of these stem cells are normally dedicated to replenishing the epidermis that ultimately protects our body. Other stem cells are former hair follicle stem cells that usually promote hair growth but will also respond to …
Pancreatic cancer has the highest mortality rate of all major cancers and is projected to become the second-leading cause of cancer-related deaths in the United States by 2030. It is especially difficult to treat because pancreatic tumors grow so quickly and are constantly evolving, making them prone to developing drug resistance. Patient-derived organoids could change …
Broccoli, not everyone likes broccoli, which is a shame because it is among the bountiful beneficial beauties coming from the cruciferous vegetable family with some compelling reasons that have been scientifically proven to help promote overall health, prevent and kill cancer cells, reduce tumors, and help prevent their spread. This vegetable has also been found …
Most experts suggest that people enjoy most things in moderation, that is because no matter how important something is, too much of anything can be bad for you. Building on this principal, scientists from EWHA Womens University are working to kill cancer with a new drug that causes calcium to build up which basically chokes …
Tumors constantly shed DNA from dying cells, which briefly circulates in the patient’s bloodstream before it is quickly broken down. Many companies have created blood tests that can pick out this tumor DNA, potentially helping doctors diagnose or monitor cancer or choose a treatment. The amount of tumor DNA circulating at any given time, however, …